N-(2-(1H-Indol-3-yl)ethyl)-2-(6-methoxynaphthalen-2-yl)propanamide
نویسندگان
چکیده
The title compound was obtained in high yield the reaction between tryptamine and naproxen. newly synthesized naproxen derivative fully analyzed characterized via 1H, 13C-NMR, UV, IR, mass spectral data.
منابع مشابه
The effect of hydrogen bonding on the conformations of 2-(1H-indol-3-yl)-2-oxoacetamide and 2-(1H-indol-3-yl)-N,N-dimethyl-2-oxoacetamide.
In the title compounds, C(10)H(8)N(2)O(2), (I), and C(12)H(12)N(2)O(2), (II), the two carbonyl groups are oriented with torsion angles of -149.3 (3) and -88.55 (15)°, respectively. The single-bond distances linking the two carbonyl groups are 1.528 (4) and 1.5298 (17) Å, respectively. In (I), the molecules are linked by an elaborate system of N-H···O hydrogen bonds, which form adjacent R(2)(2)(...
متن کاملN 2-[1-(2-Hydroxyphenyl)ethylidene]-N 2′-(1H-indol-3-ylmethylene)carbonic dihydrazide
In the crystal structure of the title compound {alternative name: 1-[1-(2-hydroxy-phen-yl)ethyl-ideneamino]-3-(1H-indol-3-ylmethyl-eneamino)urea}, C(18)H(17)N(5)O(2), the planar indole component is twisted at an angle of 63.7 (10)° with respect to the rest of the mol-ecule. This compound is one of a series being studied for biological activity. The hydr-oxy groups are involved in both intra-mol...
متن کامل2-(6-Chloro-1H-indol-3-yl)acetonitrile
In the title compound, C(10)H(7)ClN(2), the carbonitrile group is twisted away from the plane of the indole ring system [C(cy)-C(me)-C(ar)-C(ar) = -44.7 (8)°; cy = cyanide, me = methyl-ene and ar = aromatic]. In the crystal, N-H⋯N hydrogen bonds link the mol-ecules into C(7) chains propagating in [010]. Aromatic π-π stacking inter-actions [minimum centroid-centroid separation = 3.663 (3) Å] are...
متن کاملBenzyl N-[2-(1H-indol-3-yl)ethyl]dithiocarbamate
The indole and phenyl ring systems in the title compound, C(18)H(18)N(2)S(2), are nearly coplanar, the indole and phenyl planes forming a dihedral angle of 6.5 (1)°. Supra-molecular aggregation is effected by N-H⋯S, C-H⋯S, N-H⋯π and C-H⋯π inter-actions. The crystal studied exhibited inversion twinning.
متن کامل(S)-(−)-2-(1H-Indol-3-yl)-N-(1-phenylethyl)acetamide
In the title compound, C(18)H(18)N(2)O, the dihedral angle between the indole system and the phenyl ring is 17.2 (2)°. The crystal packing features two N-H⋯O hydrogen bonds, which link the mol-ecules into layers parallel to (001). The absolute configuration was determined by the synthetic procedure and was set according to the starting material.
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ژورنال
عنوان ژورنال: Molbank
سال: 2021
ISSN: ['1422-8599']
DOI: https://doi.org/10.3390/m1187